Exploring Flow Procedures for Diazonium Formation
The synthesis of diazonium salts is historically an important transformation extensively utilized in dye manufacture. However the highly reactive nature of the diazonium functionality has additionally led to the development of many new reactions including several carbon-carbon bond forming processes...
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MDPI AG
2016-07-01
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| Series: | Molecules |
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| Online Access: | http://www.mdpi.com/1420-3049/21/7/918 |
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doaj-8af90d1d2eb041b7a34e48e433e634372020-11-24T22:11:51ZengMDPI AGMolecules1420-30492016-07-0121791810.3390/molecules21070918molecules21070918Exploring Flow Procedures for Diazonium FormationTe Hu0Ian R. Baxendale1Marcus Baumann2Department of Chemistry, University of Durham, South Road, Durham DH1 3LE, UKDepartment of Chemistry, University of Durham, South Road, Durham DH1 3LE, UKDepartment of Chemistry, University of Durham, South Road, Durham DH1 3LE, UKThe synthesis of diazonium salts is historically an important transformation extensively utilized in dye manufacture. However the highly reactive nature of the diazonium functionality has additionally led to the development of many new reactions including several carbon-carbon bond forming processes. It is therefore highly desirable to determine optimum conditions for the formation of diazonium compounds utilizing the latest processing tools such as flow chemistry to take advantage of the increased safety and continuous manufacturing capabilities. Herein we report a series of flow-based procedures to prepare diazonium salts for subsequent in-situ consumption.http://www.mdpi.com/1420-3049/21/7/918diazonium saltsflow chemistrymeso reactorprocessingsupported reagent |
| collection |
DOAJ |
| language |
English |
| format |
Article |
| sources |
DOAJ |
| author |
Te Hu Ian R. Baxendale Marcus Baumann |
| spellingShingle |
Te Hu Ian R. Baxendale Marcus Baumann Exploring Flow Procedures for Diazonium Formation Molecules diazonium salts flow chemistry meso reactor processing supported reagent |
| author_facet |
Te Hu Ian R. Baxendale Marcus Baumann |
| author_sort |
Te Hu |
| title |
Exploring Flow Procedures for Diazonium Formation |
| title_short |
Exploring Flow Procedures for Diazonium Formation |
| title_full |
Exploring Flow Procedures for Diazonium Formation |
| title_fullStr |
Exploring Flow Procedures for Diazonium Formation |
| title_full_unstemmed |
Exploring Flow Procedures for Diazonium Formation |
| title_sort |
exploring flow procedures for diazonium formation |
| publisher |
MDPI AG |
| series |
Molecules |
| issn |
1420-3049 |
| publishDate |
2016-07-01 |
| description |
The synthesis of diazonium salts is historically an important transformation extensively utilized in dye manufacture. However the highly reactive nature of the diazonium functionality has additionally led to the development of many new reactions including several carbon-carbon bond forming processes. It is therefore highly desirable to determine optimum conditions for the formation of diazonium compounds utilizing the latest processing tools such as flow chemistry to take advantage of the increased safety and continuous manufacturing capabilities. Herein we report a series of flow-based procedures to prepare diazonium salts for subsequent in-situ consumption. |
| topic |
diazonium salts flow chemistry meso reactor processing supported reagent |
| url |
http://www.mdpi.com/1420-3049/21/7/918 |
| work_keys_str_mv |
AT tehu exploringflowproceduresfordiazoniumformation AT ianrbaxendale exploringflowproceduresfordiazoniumformation AT marcusbaumann exploringflowproceduresfordiazoniumformation |
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