Microtubule organization is determined by the shape of epithelial cells
Interphase microtubule organization creates a structural scaffold for cargo delivery determining cell polarity and cell shape. Here the authors show that in Drosophilaepithelia the orientation of microtubules responds to cell shape, rather than the converse, and develop a simple model to mimic this...
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| Format: | Article |
| Language: | English |
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Nature Publishing Group
2016-10-01
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| Series: | Nature Communications |
| Online Access: | https://doi.org/10.1038/ncomms13172 |
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Article |
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doaj-8af54466a4ca4304bf2d0ddec78f55a32021-05-11T11:04:48ZengNature Publishing GroupNature Communications2041-17232016-10-017111310.1038/ncomms13172Microtubule organization is determined by the shape of epithelial cellsJuan Manuel Gomez0Lyubov Chumakova1Natalia A. Bulgakova2Nicholas H. Brown3Department of Physiology, Development and Neuroscience, and the Gurdon Institute, The University of CambridgeSchool of Mathematics and Maxwell Institute for Mathematical Sciences, The University of EdinburghDepartment of Physiology, Development and Neuroscience, and the Gurdon Institute, The University of CambridgeDepartment of Physiology, Development and Neuroscience, and the Gurdon Institute, The University of CambridgeInterphase microtubule organization creates a structural scaffold for cargo delivery determining cell polarity and cell shape. Here the authors show that in Drosophilaepithelia the orientation of microtubules responds to cell shape, rather than the converse, and develop a simple model to mimic this behaviour.https://doi.org/10.1038/ncomms13172 |
| collection |
DOAJ |
| language |
English |
| format |
Article |
| sources |
DOAJ |
| author |
Juan Manuel Gomez Lyubov Chumakova Natalia A. Bulgakova Nicholas H. Brown |
| spellingShingle |
Juan Manuel Gomez Lyubov Chumakova Natalia A. Bulgakova Nicholas H. Brown Microtubule organization is determined by the shape of epithelial cells Nature Communications |
| author_facet |
Juan Manuel Gomez Lyubov Chumakova Natalia A. Bulgakova Nicholas H. Brown |
| author_sort |
Juan Manuel Gomez |
| title |
Microtubule organization is determined by the shape of epithelial cells |
| title_short |
Microtubule organization is determined by the shape of epithelial cells |
| title_full |
Microtubule organization is determined by the shape of epithelial cells |
| title_fullStr |
Microtubule organization is determined by the shape of epithelial cells |
| title_full_unstemmed |
Microtubule organization is determined by the shape of epithelial cells |
| title_sort |
microtubule organization is determined by the shape of epithelial cells |
| publisher |
Nature Publishing Group |
| series |
Nature Communications |
| issn |
2041-1723 |
| publishDate |
2016-10-01 |
| description |
Interphase microtubule organization creates a structural scaffold for cargo delivery determining cell polarity and cell shape. Here the authors show that in Drosophilaepithelia the orientation of microtubules responds to cell shape, rather than the converse, and develop a simple model to mimic this behaviour. |
| url |
https://doi.org/10.1038/ncomms13172 |
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