Tizoxanide pyridine monosolvate

In the title compound [systematic name: 2-hydroxy-N-(5-nitro-1,3-thiazol-2-yl)benzamide pyridine monosolvate], C10H7N3O4S·C5H5N, the dihedral angle between the pyridine and benzamide rings is 80.55 (7)°. An intamolecular O—H...N hydrogen bond occ...

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Bibliographic Details
Main Authors: Huaqin Zheng, Hui Deng, Yunyun Chen, Ding Li
Format: Article
Language:English
Published: International Union of Crystallography 2012-05-01
Series:Acta Crystallographica Section E
Online Access:http://scripts.iucr.org/cgi-bin/paper?S1600536812016133
Description
Summary:In the title compound [systematic name: 2-hydroxy-N-(5-nitro-1,3-thiazol-2-yl)benzamide pyridine monosolvate], C10H7N3O4S·C5H5N, the dihedral angle between the pyridine and benzamide rings is 80.55 (7)°. An intamolecular O—H...N hydrogen bond occurs in the tizoxanide. In the crystal, the components are linked by an O–H...N hydrogen bond, forming a zigzag chain along the c axis. Aromatic π–π interactions between inversion-related pyridine rings [centroid–centroid distance = 3.803 (6) Å] are also observed.
ISSN:1600-5368