Tepotinib Inhibits the Epithelial–Mesenchymal Transition and Tumor Growth of Gastric Cancers by Increasing GSK3β, E-Cadherin, and Mucin 5AC and 6 Levels

Aberrant expression of mucins (MUCs) can promote the epithelial–mesenchymal transition (EMT), which leads to enhanced tumorigenesis. Carcinogenesis-related pathways involving c-MET and β-catenin are associated with MUCs. In this study, we characterized the expression of EMT-relevant proteins includi...

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Bibliographic Details
Main Authors: Sung-Hwa Sohn, Hee Jung Sul, Bohyun Kim, Bum Jun Kim, Hyeong Su Kim, Dae Young Zang
Format: Article
Language:English
Published: MDPI AG 2020-08-01
Series:International Journal of Molecular Sciences
Subjects:
EMT
Online Access:https://www.mdpi.com/1422-0067/21/17/6027