GapClust is a light-weight approach distinguishing rare cells from voluminous single cell expression profiles

While rare cell type identification is indispensable in single cell studies, powerful tools with high detection accuracy and computational efficiency are still lacking. Here, the authors propose a light-weight algorithm which can distinguish rare cell types from voluminous single cell expression pro...

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Bibliographic Details
Main Authors: Botao Fa, Ting Wei, Yuan Zhou, Luke Johnston, Xin Yuan, Yanran Ma, Yue Zhang, Zhangsheng Yu
Format: Article
Language:English
Published: Nature Publishing Group 2021-07-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-021-24489-8
Description
Summary:While rare cell type identification is indispensable in single cell studies, powerful tools with high detection accuracy and computational efficiency are still lacking. Here, the authors propose a light-weight algorithm which can distinguish rare cell types from voluminous single cell expression profiles.
ISSN:2041-1723