Natural and Synthetic Modulators of the TRPM7 Channel

Natural and Synthetic Modulators of the TRPM7 Channel

Transient receptor potential cation channel subfamily M member 7 (TRPM7) is a bi-functional protein comprising a TRP ion channel segment linked to an α-type protein kinase domain. Genetic inactivation of TRPM7 revealed its central role in magnesium metabolism, cell motility, proliferation and differ...

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Bibliographic Details
Main Authors: Vladimir Chubanov, Sebastian Schäfer, Silvia Ferioli, Thomas Gudermann
Format: Article
Language:English
Published: MDPI AG 2014-11-01
Series:Cells
Subjects:
TRPM7
TRPM6
TRP channel
α-kinase
magnesium
calcium
Online Access:http://www.mdpi.com/2073-4409/3/4/1089

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