Route of Vaccine Administration Influences the Impact of Fms-Like Tyrosine Kinase 3 Ligand (Flt3L) on Chlamydial-Specific Protective Immune Responses

Route of Vaccine Administration Influences the Impact of Fms-Like Tyrosine Kinase 3 Ligand (Flt3L) on Chlamydial-Specific Protective Immune Responses

We tested the hypothesis that the impact of the Fms-like tyrosine kinase 3-ligand (Flt3L; FL) on recombinant Vibrio cholerae ghost (rVCG) vaccine-induced chlamydial immunity is influenced by route of vaccine delivery. Female C57BL/6J mice were immunized rectally (IR) or intramuscularly (IM) with rVC...

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Bibliographic Details
Main Authors: Roshan Pais, Yusuf Omosun, Joseph U. Igietseme, Kohtaro Fujihashi, Francis O. Eko
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-07-01
Series:Frontiers in Immunology
Subjects:
Chlamydia trachomatis
C. muridarum
PmpD
PorB
Flt3L
vaccine delivery route
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2019.01577/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2019.01577/full

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