Differences in anti-malarial activity of 4-aminoalcohol quinoline enantiomers and investigation of the presumed underlying mechanism of action
<p>Abstract</p> <p>Background</p> <p>A better anti-malarial efficiency and lower neurotoxicity have been reported for mefloquine (MQ) (+)- enantiomer. However, the importance of stereoselectivity remains poorly understood as the anti-malarial activity of pure enantiomer...
Main Authors: | Mullié Catherine, Jonet Alexia, Desgrouas Camille, Taudon Nicolas, Sonnet Pascal |
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Format: | Article |
Language: | English |
Published: |
BMC
2012-03-01
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Series: | Malaria Journal |
Subjects: | |
Online Access: | http://www.malariajournal.com/content/11/1/65 |
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