Differences in anti-malarial activity of 4-aminoalcohol quinoline enantiomers and investigation of the presumed underlying mechanism of action

<p>Abstract</p> <p>Background</p> <p>A better anti-malarial efficiency and lower neurotoxicity have been reported for mefloquine (MQ) (+)- enantiomer. However, the importance of stereoselectivity remains poorly understood as the anti-malarial activity of pure enantiomer...

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Bibliographic Details
Main Authors: Mullié Catherine, Jonet Alexia, Desgrouas Camille, Taudon Nicolas, Sonnet Pascal
Format: Article
Language:English
Published: BMC 2012-03-01
Series:Malaria Journal
Subjects:
Online Access:http://www.malariajournal.com/content/11/1/65