Paraoxonase 2 Induces a Phenotypic Switch in Macrophage Polarization Favoring an M2 Anti-Inflammatory State

Paraoxonase 2 Induces a Phenotypic Switch in Macrophage Polarization Favoring an M2 Anti-Inflammatory State

Inflammatory processes are involved in atherosclerosis development. Macrophages play a major role in the early atherogenesis, and they are present in the atherosclerotic lesion in two phenotypes: proinflammatory (M1) or anti-inflammatory (M2). Paraoxonase 2 (PON2) is expressed in macrophages, and it...

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Bibliographic Details
Main Authors:	Marie Koren-Gluzer, Mira Rosenblat, Tony Hayek
Format:	Article
Language:	English
Published:	Hindawi Limited 2015-01-01
Series:	International Journal of Endocrinology
Online Access:	http://dx.doi.org/10.1155/2015/915243

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