Epidemiologic trends in lung cancer over two decades in Northern Greece: an analysis of bronchoscopic data

Background and Aim. The relative frequency of histological subtypes of lung cancer in Europe has changed dramatically during the 20th century. The aim of this study was to explore the changing epidemiology of lung cancer in Northern Greece over the last two decades. Methods. From the extensive datab...

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Main Authors: T. Kontakiotis, N. Manolakoglou, F. Zoglopitis, D. Iakovidis, L. Sacas, A. Papagiannis, A. Mandrali, D. Papakosta, P. Argyropoulou, D. Bouros
Format: Article
Language:English
Published: PAGEPress Publications 2016-01-01
Series:Monaldi Archives for Chest Disease
Subjects:
Online Access:https://www.monaldi-archives.org/index.php/macd/article/view/346
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spelling doaj-8ab1ca4dbeee40b88438f518e7eeb42a2020-11-25T00:07:13ZengPAGEPress PublicationsMonaldi Archives for Chest Disease1122-06432532-52642016-01-0171410.4081/monaldi.2009.346Epidemiologic trends in lung cancer over two decades in Northern Greece: an analysis of bronchoscopic dataT. Kontakiotis0N. Manolakoglou1F. Zoglopitis2D. Iakovidis3L. Sacas4A. Papagiannis5A. Mandrali6D. Papakosta7P. Argyropoulou8D. Bouros9Bronchoscopy Unit, Aristotle University of ThessalonikiRespiratory Failure Unit, Aristotle University of ThessalonikiBronchoscopy Unit, Aristotle University of ThessalonikiBronchoscopy Unit, Aristotle University of ThessalonikiHistopathology Department, G. Papanicolaou General Hospital, Exochi, ThessalonikiBronchoscopy Unit, Aristotle University of ThessalonikiCytology, G. Papanicolaou Geneneral Hospital, Exochi, ThessalonikiBronchoscopy Unit, Aristotle University of ThessalonikiRespiratory Failure Unit, Aristotle University of ThessalonikiDepartment of Pneumonology, Medical School Democritus University of Thrace and University Hospital of Alexandroupolis, AlexandroupolisBackground and Aim. The relative frequency of histological subtypes of lung cancer in Europe has changed dramatically during the 20th century. The aim of this study was to explore the changing epidemiology of lung cancer in Northern Greece over the last two decades. Methods. From the extensive database of the Bronchoscopy Unit of the G. Papanicolaou General Hospital, Thessaloniki, Greece, we identified all patients with a histologic and/or cytologic report positive for lung cancer over two consecutive decades. Results. Between 1/1/1986 and 31/12/2005 we identified 9981 patients with specimens positive for lung cancer. A significant increase in mean patient age was observed during the second decade (64.8±9.4 vs. 62.1±8.9, p=0.001). Men developed lung cancer ten times more often than women. The predominant histological type was squamous cell cancer in males (4203 cases, 45.7%) and adenocarcinoma (418 cases, 52.6%) in females. The number of lung cancer cases was significantly higher during the second decade compared to the first decade (5766 cases [57.8%] vs. 4215 cases [42.2%], respectively, p<0.001). There was a significant decrease in the percentage of squamous cell carcinoma in males in the second decade (2317 cases [44.1%] vs. 1886 cases [48.0%], p<0.001), and an increase in adenocarcinoma (1021 cases [19.4%] vs. 609 [11.6%], p<0.001). In females, the relative incidence of adenocarcinoma was decreased and that of squamous cell carcinoma was increased, but not significantly. There was no obvious change in the incidence of small cell lung cancer. Neoplastic lesions were most often located in the upper lobes. Conclusion. The number of lung cancer cases has increased in the last decade. Squamous lung cancer appears to be decreasing in men and increasing in women. Adenocarcinoma appears to be increasing in men and decreasing in women. There appears to be no change in small cell lung cancer. During the second decade there has been a significant decrease in the male: female ratio.https://www.monaldi-archives.org/index.php/macd/article/view/346Lung cancerEpidemiologyBronchoscopyAdenocarcinomaSquamous cell carcinomaSmall cell carcinoma
collection DOAJ
language English
format Article
sources DOAJ
author T. Kontakiotis
N. Manolakoglou
F. Zoglopitis
D. Iakovidis
L. Sacas
A. Papagiannis
A. Mandrali
D. Papakosta
P. Argyropoulou
D. Bouros
spellingShingle T. Kontakiotis
N. Manolakoglou
F. Zoglopitis
D. Iakovidis
L. Sacas
A. Papagiannis
A. Mandrali
D. Papakosta
P. Argyropoulou
D. Bouros
Epidemiologic trends in lung cancer over two decades in Northern Greece: an analysis of bronchoscopic data
Monaldi Archives for Chest Disease
Lung cancer
Epidemiology
Bronchoscopy
Adenocarcinoma
Squamous cell carcinoma
Small cell carcinoma
author_facet T. Kontakiotis
N. Manolakoglou
F. Zoglopitis
D. Iakovidis
L. Sacas
A. Papagiannis
A. Mandrali
D. Papakosta
P. Argyropoulou
D. Bouros
author_sort T. Kontakiotis
title Epidemiologic trends in lung cancer over two decades in Northern Greece: an analysis of bronchoscopic data
title_short Epidemiologic trends in lung cancer over two decades in Northern Greece: an analysis of bronchoscopic data
title_full Epidemiologic trends in lung cancer over two decades in Northern Greece: an analysis of bronchoscopic data
title_fullStr Epidemiologic trends in lung cancer over two decades in Northern Greece: an analysis of bronchoscopic data
title_full_unstemmed Epidemiologic trends in lung cancer over two decades in Northern Greece: an analysis of bronchoscopic data
title_sort epidemiologic trends in lung cancer over two decades in northern greece: an analysis of bronchoscopic data
publisher PAGEPress Publications
series Monaldi Archives for Chest Disease
issn 1122-0643
2532-5264
publishDate 2016-01-01
description Background and Aim. The relative frequency of histological subtypes of lung cancer in Europe has changed dramatically during the 20th century. The aim of this study was to explore the changing epidemiology of lung cancer in Northern Greece over the last two decades. Methods. From the extensive database of the Bronchoscopy Unit of the G. Papanicolaou General Hospital, Thessaloniki, Greece, we identified all patients with a histologic and/or cytologic report positive for lung cancer over two consecutive decades. Results. Between 1/1/1986 and 31/12/2005 we identified 9981 patients with specimens positive for lung cancer. A significant increase in mean patient age was observed during the second decade (64.8±9.4 vs. 62.1±8.9, p=0.001). Men developed lung cancer ten times more often than women. The predominant histological type was squamous cell cancer in males (4203 cases, 45.7%) and adenocarcinoma (418 cases, 52.6%) in females. The number of lung cancer cases was significantly higher during the second decade compared to the first decade (5766 cases [57.8%] vs. 4215 cases [42.2%], respectively, p<0.001). There was a significant decrease in the percentage of squamous cell carcinoma in males in the second decade (2317 cases [44.1%] vs. 1886 cases [48.0%], p<0.001), and an increase in adenocarcinoma (1021 cases [19.4%] vs. 609 [11.6%], p<0.001). In females, the relative incidence of adenocarcinoma was decreased and that of squamous cell carcinoma was increased, but not significantly. There was no obvious change in the incidence of small cell lung cancer. Neoplastic lesions were most often located in the upper lobes. Conclusion. The number of lung cancer cases has increased in the last decade. Squamous lung cancer appears to be decreasing in men and increasing in women. Adenocarcinoma appears to be increasing in men and decreasing in women. There appears to be no change in small cell lung cancer. During the second decade there has been a significant decrease in the male: female ratio.
topic Lung cancer
Epidemiology
Bronchoscopy
Adenocarcinoma
Squamous cell carcinoma
Small cell carcinoma
url https://www.monaldi-archives.org/index.php/macd/article/view/346
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