Reactive oxygen species mediate cognitive deficits in experimental temporal lobe epilepsy

Reactive oxygen species mediate cognitive deficits in experimental temporal lobe epilepsy

Cognitive dysfunction is an important comorbidity of temporal lobe epilepsy (TLE). However, no targeted therapies are available and the mechanisms underlying cognitive impairment, specifically deficits in learning and memory associated with TLE remain unknown. Oxidative stress is known to occur in t...

Full description

Bibliographic Details
Main Authors:	Jennifer N. Pearson, Shane Rowley, Li-Ping Liang, Andrew M. White, Brian J. Day, Manisha Patel
Format:	Article
Language:	English
Published:	Elsevier 2015-10-01
Series:	Neurobiology of Disease
Subjects:	Epilepsy Learning and memory Oxidative stress Reactive oxygen species Pilocarpine Mitochondrial dysfunction
Online Access:	http://www.sciencedirect.com/science/article/pii/S0969996115300115

Similar Items

Mitochondrial respiration deficits driven by reactive oxygen species in experimental temporal lobe epilepsy
by: Shane Rowley, et al.
Published: (2015-03-01)

Selective hyperactivation of JNK2 in an animal model of temporal lobe epilepsy
by: A.N. Parikh, et al.
Published: (2020-06-01)

Synaptic Reshaping and Neuronal Outcomes in the Temporal Lobe Epilepsy
by: Elisa Ren, et al.
Published: (2021-04-01)

Changes in hippocampal volume are correlated with cell loss but not with seizure frequency in two chronic models of temporal lobe epilepsy
by: Roberson Saraiva Polli, et al.
Published: (2014-07-01)

Functional role of mGluR1 and mGluR4 in pilocarpine-induced temporal lobe epilepsy
by: J. Pitsch, et al.
Published: (2007-06-01)

Temporal and spatial increase of reactive nitrogen species in the kainate model of temporal lobe epilepsy
by: Kristen Ryan, et al.
Published: (2014-04-01)

Perirhinal cortex and temporal lobe epilepsy
by: Giuseppe eBiagini, et al.
Published: (2013-08-01)

Phase-amplitude coupling and epileptogenesis in an animal model of mesial temporal lobe epilepsy
by: Soheila Samiee, et al.
Published: (2018-06-01)

Quantitative analysis on the origins of morphologically abnormal cells in temporal lobe epilepsy
by: Singh, Shatrunjai P.
Published: (2015)

Système supramammillaro- hippocampique : propriétés anatomiques et neurochimiques; plasticité dans un modèle d'épilepsie du lobe temporal
by: Soussi, Rabia
Published: (2011)

Déficits cognitifs et altération de l'activité de réseau au cours de l'épileptogenèse dans un modèle expérimental d'épilepsie du lobe temporal
by: Chauviere, Laëtitia
Published: (2010)

Expressional analysis of the astrocytic Kir4.1 channel in a pilocarpine-induced temporal lobe epilepsy model
by: Yuki eNagao, et al.
Published: (2013-07-01)

Changes in the sensitivity of GABAA current rundown to drug treatments in a model of temporal lobe epilepsy
by: Pierangelo eCifelli, et al.
Published: (2013-07-01)

Parawixin2 Protects Hippocampal Cells in Experimental Temporal Lobe Epilepsy
by: José Luiz Liberato, et al.
Published: (2018-11-01)

Purslane protects against the reproductive toxicity of carbamazepine treatment in pilocarpine-induced epilepsy model
by: Widad Makhdour Al-Bishri, et al.
Published: (2017-04-01)

Anticonvulsant effects of antiaris toxicaria aqueous extract: investigation using animal models of temporal lobe epilepsy
by: Priscilla Kolibea Mante, et al.
Published: (2017-04-01)

In vitro ictogenesis and parahippocampal networks in a rodent model of temporal lobe epilepsy
by: G. Panuccio, et al.
Published: (2010-09-01)

Chemical biomarkers of epileptogenesis and ictogenesis in experimental epilepsy
by: Hiram Luna-Munguia, et al.
Published: (2019-01-01)

Epilepsy in a Mitochondrial Disorder
by: J Gordon Millichap
Published: (1992-02-01)

Homeostasis or channelopathy? Acquired cell type-specific ion channel changes in temporal lobe epilepsy and their antiepileptic potential
by: Jakob eWolfart, et al.
Published: (2015-06-01)

Time-dependent evolution of seizures in a model of mesial temporal lobe epilepsy
by: Charles Behr, et al.
Published: (2017-10-01)

Neural circuit mechanisms of posttraumatic epilepsy
by: Robert F Hunt, et al.
Published: (2013-06-01)

Saikosaponin A modulates remodeling of Kv4.2-mediated A-type voltage-gated potassium currents in rat chronic temporal lobe epilepsy
by: Hong Y, et al.
Published: (2018-09-01)

High-frequency (80–500 Hz) oscillations and epileptogenesis in temporal lobe epilepsy
by: Maxime Lévesque, et al.
Published: (2011-06-01)

Modeling of chronic epilepsy in animals through chemical methods
by: E. V. Egorova, et al.
Published: (2020-01-01)

Assessment of the progressive nature of cell damage in the pilocarpine model of epilepsy
by: L. Covolan, et al.
Published: (2006-07-01)

Altered Protein Profiles During Epileptogenesis in the Pilocarpine Mouse Model of Temporal Lobe Epilepsy
by: Md. Mahiuddin Ahmed, et al.
Published: (2021-05-01)

Effects of Lacosamide Treatment on Epileptogenesis, Neuronal Damage and Behavioral Comorbidities in a Rat Model of Temporal Lobe Epilepsy
by: Michaela Shishmanova-Doseva, et al.
Published: (2021-04-01)

Sensitivity of Rodent Microglia to Kynurenines in Models of Epilepsy and Inflammation In Vivo and In Vitro: Microglia Activation is Inhibited by Kynurenic Acid and the Synthetic Analogue SZR104
by: Noémi Lajkó, et al.
Published: (2020-12-01)

Preoperative visual field deficits in temporal lobe epilepsy
by: Sanjeet S. Grewal, et al.
Published: (2017-01-01)

Excitatory synaptic transmission in hippocampal area CA1 is enhanced then reduced as chronic epilepsy progresses
by: Benjamin Owen, et al.
Published: (2021-07-01)

The Effects of Bone Marrow Stromal Cells Therapy on the Improvement of Epilepsy Model in Rat Induced by pilocarpine
by: Ali Reza Abdani-Pour, et al.
Published: (2008-01-01)

Neuropsychological deficits in temporal lobe epilepsy: A comprehensive review
by: Fengqing Zhao, et al.
Published: (2014-01-01)

Spatial memory deficits in juvenile rats with pilocarpine induced temporal lobe epilepsy
by: Orbán-Kis K, et al.
Published: (2014-10-01)

Adenosine A1 Receptor Agonist (R-PIA) before Pilocarpine Modulates Pro- and Anti-Apoptotic Factors in an Animal Model of Epilepsy
by: Daniele Suzete Persike, et al.
Published: (2021-04-01)

The effect of amygdala low-frequency stimulation on inter-hippocampal connectivity in the pilocarpine model of epilepsy
by: Mihály István, et al.
Published: (2021-03-01)

The role of the inherited genetic background on the consequences of lithium-pilocarpine status epilepticus: Study in Genetic Absence Epilepsy Rats from Strasbourg and Wistar audiogenic rats
by: Ryosuke Hanaya, et al.
Published: (2008-09-01)

Plasma cysteine/cystine redox couple disruption in animal models of temporal lobe epilepsy
by: Li-Ping Liang, et al.
Published: (2016-10-01)

Altered cardiac structure and function is related to seizure frequency in a rat model of chronic acquired temporal lobe epilepsy
by: Kim L. Powell, et al.
Published: (2021-11-01)

Surgical Considerations of Intractable Mesial Temporal Lobe Epilepsy
by: Warren W. Boling
Published: (2018-02-01)