Aurora kinase A (AURKA) promotes the progression and imatinib resistance of advanced gastrointestinal stromal tumors

Aurora kinase A (AURKA) promotes the progression and imatinib resistance of advanced gastrointestinal stromal tumors

Abstract Background Gastrointestinal stromal tumor (GIST) is a common tumor that originates from the alimentary system mesenchyme. Compared to typical gastrointestinal carcinomas, GISTs exhibit unique malignant behaviors. Bioinformatic tools and subsequent experiments were applied to investigate nov...

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Bibliographic Details
Main Authors: Xiaobin Cheng, Jinhai Wang, Sen Lu, Weina Fan, Weilin Wang
Format: Article
Language:English
Published: BMC 2021-07-01
Series:Cancer Cell International
Subjects:
AURKA
Progression
Imatinib resistance
Gastrointestinal stromal tumors
Online Access:https://doi.org/10.1186/s12935-021-02111-7

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