Effect of Caloric Restriction on the in vivo Functional Properties of Aging Microglia

Throughout the lifespan, microglia, the primary innate immune cells of the brain, fulfill a plethora of homeostatic as well as active immune defense functions, and their aging-induced dysfunctionality is now considered as a key trigger of aging-related brain disorders. Recent evidence suggests that...

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Bibliographic Details
Main Authors: Maria Olmedillas del Moral, Nicole Fröhlich, Katherine Figarella, Nima Mojtahedi, Olga Garaschuk
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-04-01
Series:Frontiers in Immunology
Subjects:
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2020.00750/full