Cell Based Therapy for Type 1 Diabetes: Should We Take Hyperglycemia Into Account?

Cell Based Therapy for Type 1 Diabetes: Should We Take Hyperglycemia Into Account?

Diabetes mellitus is characterized by long standing hyperglycemia leading to numerous life-threatening complications. For type 1 diabetes mellitus, resulting from selective destruction of insulin producing cells by exaggerated immune reaction, the only effective therapy remains exogenous insulin adm...

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Bibliographic Details
Main Authors: Anna Grohová, Klára Dáňová, Radek Špíšek, Lenka Palová-Jelínková
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-02-01
Series:Frontiers in Immunology
Subjects:
dendritic cells
immune tolerance
cell-based therapy
diabetes mellitus
hyperglycemia
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2019.00079/full

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