PA28α/β Promote Breast Cancer Cell Invasion and Metastasis via Down-Regulation of CDK15

PA28α/β activated immunoproteasome frequently participates in MHC class I antigen processing, however, whether it is involved in breast tumor progression remains largely unclear. Here, our evidences show that PA28α/β proteins are responsible for breast cancer cell migration, invasion, and metastasis...

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Bibliographic Details
Main Authors: Shengnan Li, Xiaoqin Dai, Kunxiang Gong, Kai Song, Fang Tai, Jian Shi
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-11-01
Series:Frontiers in Oncology
Subjects:
Online Access:https://www.frontiersin.org/article/10.3389/fonc.2019.01283/full