Domestic chickens activate a piRNA defense against avian leukosis virus

Domestic chickens activate a piRNA defense against avian leukosis virus

PIWI-interacting RNAs (piRNAs) protect the germ line by targeting transposable elements (TEs) through the base-pair complementarity. We do not know how piRNAs co-evolve with TEs in chickens. Here we reported that all active TEs in the chicken germ line are targeted by piRNAs, and as TEs lose their a...

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Bibliographic Details
Main Authors: Yu Huining Sun, Li Huitong Xie, Xiaoyu Zhuo, Qiang Chen, Dalia Ghoneim, Bin Zhang, Jarra Jagne, Chengbo Yang, Xin Zhiguo Li
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2017-04-01
Series:eLife
Subjects:
piRNA
endogenous retrovirus
PIWI
transposable element
White Leghorn
Red Jungle Fowl
Online Access:https://elifesciences.org/articles/24695

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