Towards a genetic AIDS vaccine

<p>Abstract</p> <p>We discuss a recent Nature Medicine publication by Philip Johnson and co-workers (Vector-mediated gene transfer engenders long-lived neutralizing activity and protection against SIV infection in monkeys. <it>Nat. Med</it>. 2009, 15: 901-906) in which...

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Bibliographic Details
Main Authors: Berkhout Ben, Bordería Antonia V
Format: Article
Language:English
Published: BMC 2009-10-01
Series:Retrovirology
Online Access:http://www.retrovirology.com/content/6/1/93
Description
Summary:<p>Abstract</p> <p>We discuss a recent Nature Medicine publication by Philip Johnson and co-workers (Vector-mediated gene transfer engenders long-lived neutralizing activity and protection against SIV infection in monkeys. <it>Nat. Med</it>. 2009, 15: 901-906) in which an effective HIV-1 vaccine was designed that is based on gene therapy. The introduced gene produces an antibody-like immunoadhesin in the blood that neutralizes the virus.</p>
ISSN:1742-4690