Effect of soluble interleukin-6 receptor α and interleukin-6 secreted by polymorphonuclear leukocytes on tumor necrosis factor-α expression and its production by peripheral blood mononuclear cells

Background: It has recently been shown that soluble interleukin-6 receptor (sIL-6R) alone or complexed with interleukin (IL)-6, besides their regulatory role in a wide variety of both normal and abnormal biologic reactions mediated by IL-6, could be an effective stimulator of the cell function.

Bibliographic Details
Main Author: E. Jablonska
Format: Article
Language:English
Published: Hindawi Limited 2002-01-01
Series:Mediators of Inflammation
Online Access:http://dx.doi.org/10.1080/09629350210000015746

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