Construction of a Promising Tumor-Infiltrating CD8+ T Cells Gene Signature to Improve Prediction of the Prognosis and Immune Response of Uveal Melanoma

Construction of a Promising Tumor-Infiltrating CD8+ T Cells Gene Signature to Improve Prediction of the Prognosis and Immune Response of Uveal Melanoma

BackgroundCD8+ T cells work as a key effector of adaptive immunity and are closely associated with immune response for killing tumor cells. It is crucial to understand the role of tumor-infiltrating CD8+ T cells in uveal melanoma (UM) to predict the prognosis and response to immunotherapy.Materials...

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Bibliographic Details
Main Authors: Yifang Sun, Jian Wu, Yonggang Yuan, Yumin Lu, Ming Luo, Ling Lin, Shengsheng Ma
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-05-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
CD8+ T cells
immune-related genes
immunotherapy
prognosis
uveal melanoma
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2021.673838/full

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