Annexin A1 Mimetic Peptide Ac2-26 Modulates the Function of Murine Colonic and Human Mast Cells

Annexin A1 Mimetic Peptide Ac2-26 Modulates the Function of Murine Colonic and Human Mast Cells

Mast cells (MCs) are main effector cells in allergic inflammation and after activation, they release stored (histamine, heparin, proteases) and newly synthesized (lipid mediators and cytokines) substances. In the gastrointestinal tract the largest MC population is located in the lamina propria and s...

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Bibliographic Details
Main Authors: Marcia Pereira Oliveira, Janesly Prates, Alexandre Dantas Gimenes, Silvia Graciela Correa, Sonia Maria Oliani
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-09-01
Series:Frontiers in Immunology
Subjects:
mast cell (MC)
compound 48/80
human MC line (HMC-1)
colon explant culture
annexin A1
IL-4
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.689484/full

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