Insulin-Independent Reversal of Type-1 Diabetes Following Transplantation of Adult Brown Adipose Tissue Supplemented With IGF-1

Insulin-Independent Reversal of Type-1 Diabetes Following Transplantation of Adult Brown Adipose Tissue Supplemented With IGF-1

Background. As our previous publications show, it is feasible to reverse type 1 diabetes (T1D) without insulin in multiple mouse models, through transplantation of embryonic brown adipose tissue (BAT) in the subcutaneous space. Embryonic BAT transplants result in rapid and long-lasting euglycemia ac...

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Bibliographic Details
Main Authors:	Subhadra C. Gunawardana, PhD, David W. Piston, PhD
Format:	Article
Language:	English
Published:	Wolters Kluwer 2019-11-01
Series:	Transplantation Direct
Online Access:	http://journals.lww.com/transplantationdirect/fulltext/10.1097/TXD.0000000000000945

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