Repetitive mild traumatic brain injury in mice triggers a slowly developing cascade of long-term and persistent behavioral deficits and pathological changes

Repetitive mild traumatic brain injury in mice triggers a slowly developing cascade of long-term and persistent behavioral deficits and pathological changes

Abstract We have previously reported long-term changes in the brains of non-concussed varsity rugby players using magnetic resonance spectroscopy (MRS), diffusion tensor imaging (DTI) and functional magnetic imaging (fMRI). Others have reported cognitive deficits in contact sport athletes that have...

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Bibliographic Details
Main Authors: Xiaoyun Xu, Matthew Cowan, Flavio Beraldo, Amy Schranz, Patrick McCunn, Nicole Geremia, Zalman Brown, Maitray Patel, Karen L. Nygard, Reza Khazaee, Lihong Lu, Xingyu Liu, Michael J. Strong, Gregory A. Dekaban, Ravi Menon, Robert Bartha, Mark Daley, Haojie Mao, Vania Prado, Marco A. M. Prado, Lisa Saksida, Tim Bussey, Arthur Brown
Format: Article
Language:English
Published: BMC 2021-04-01
Series:Acta Neuropathologica Communications
Subjects:
Concussion
5-Choice serial reaction time test
White matter pathology
Tauopathy
Experimental brain injury
Traumatic encephalopathy
Online Access:https://doi.org/10.1186/s40478-021-01161-2

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