Comparison of the NMR and the Acid Value Determination Methods for Quality Control of Input Polysorbates
Polysorbates (PS) are the most common non-ionic surfactants used in protein formulations. Their degradation has been studied intensively in recent years. Ester bond hydrolysis is one of many pathways of PS degradation that can lead to accumulation of free fatty acids (FFAs) and particle formation. T...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
Slovenian Chemical Society
2019-12-01
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Series: | Acta Chimica Slovenica |
Subjects: | |
Online Access: | https://journals.matheo.si/index.php/ACSi/article/view/5144 |