Dual short upstream open reading frames control translation of a herpesviral polycistronic mRNA.
The Kaposi's sarcoma-associated herpesvirus (KSHV) protein kinase, encoded by ORF36, functions to phosphorylate cellular and viral targets important in the KSHV lifecycle and to activate the anti-viral prodrug ganciclovir. Unlike the vast majority of mapped KSHV genes, no viral transcript has b...
Main Authors: | Lisa M Kronstad, Kevin F Brulois, Jae U Jung, Britt A Glaunsinger |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2013-01-01
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Series: | PLoS Pathogens |
Online Access: | http://europepmc.org/articles/PMC3561293?pdf=render |
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