Phytochemical Activation of Nrf2 Protects Human Coronary Artery Endothelial Cells against an Oxidative Challenge

Activation of NF-E2-related factor 2 (Nrf2) is a potential therapeutic intervention against endothelial cell oxidative stress and associated vascular disease. We hypothesized that treatment with the phytochemicals in the patented dietary supplement Protandim would induce Nrf2 nuclear localization an...

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Bibliographic Details
Main Authors: Elise L. Donovan, Joe M. McCord, Danielle J. Reuland, Benjamin F. Miller, Karyn L. Hamilton
Format: Article
Language:English
Published: Hindawi Limited 2012-01-01
Series:Oxidative Medicine and Cellular Longevity
Online Access:http://dx.doi.org/10.1155/2012/132931