Development and Validation of a HPLC Method for Determination of Pefloxacin in Tablet and Human Plasma

Development and Validation of a HPLC Method for Determination of Pefloxacin in Tablet and Human Plasma

Objective(s)Developing and validating a simple, efficient, reproducible and economic reversed phase high performance liquid chromatographic (RP-HPLC) method for the quantitative determination of pefloxacin in bulk material, tablets and in human plasma. Materials and MethodsA shim-pack CLC-ODS column...

Full description

Bibliographic Details
Main Authors:	Shahnaz Gauhar, S. Ayub Ali, Harris Shoaib, S. Baqir Naqvi, Iyad Naeem Muhammad
Format:	Article
Language:	English
Published:	Mashhad University of Medical Sciences 2009-03-01
Series:	Iranian Journal of Basic Medical Sciences
Subjects:	Antibiotics Fluoroquinolone High Performance Liquid Chromatography Pefloxacin Quantitative analysis Validation studies
Online Access:	http://www.mums.ac.ir/shares/basic_medical/basicmedjou/88/spring/gauhar.pdf

Similar Items

Pefloxacin as a surrogate marker for quinolone susceptibility in Salmonella enterica serovars Typhi & Paratyphi A in India
by: Priyanka Sharma, et al.
Published: (2017-01-01)

Pefloxacin Residues in Tissues and Organs of Treated Rabbits
by: Mona Abou El-Nil
Published: (2008-03-01)

Tissue dyslipidemia in salmonella-infected rats treated with amoxillin and pefloxacin
by: Rotimi Solomon O, et al.
Published: (2012-11-01)

Quantitative determination of pefloxacin mesylate by residual-base neutralisation method
by: HULIKALCHANDRA SHEKAR PRAMEELA, et al.
Published: (2004-05-01)

Oral Bioavailability and Plasma Disposition of Pefloxacin in Healthy Broiler Chickens
by: María-Aránzazu Martínez, et al.
Published: (2017-05-01)

Herb drug interaction: effect of Manix® on pharmacokinetic parameters of pefloxacin in rat model
by: Nduka Sunday Odunke, et al.
Published: (2014-05-01)

Comparable Bioavailability and Disposition of Pefloxacin in Patients with Cystic Fibrosis and Healthy Volunteers Assessed via Population Pharmacokinetics
by: Jürgen B. Bulitta, et al.
Published: (2019-07-01)

Comparative Assessment of Modern Fluoroquinolones Efficacy in Experimental Tularemia Treatment
by: T. A. Bondareva, et al.
Published: (2008-06-01)

Development of an indirect enzyme-linked immunosorbent assay and lateral-flow test strips for pefloxacin and its analogues in chicken muscle samples
by: Daniel Mukunzi, et al.
Published: (2018-01-01)

Quinolone Susceptibility in Salmonella Isolates Based on Minimum Inhibitory Concentration Determination
by: Varsha Gupta, et al.
Published: (2020-12-01)

Simultaneous Determinaton of Fluoroquinolones in Feed by Liquid Chromatography with Fluorescence Detection
by: Gbylik Małgorzata, et al.
Published: (2012-09-01)

Application of HPLC-DAD for the quantification of Lycorine in Galanthus elwesii Hook
by: Ahmet Emir, et al.
Published: (2017-04-01)

Quantitative determination of perfloxacin mesylate by residual-base neutralisation method
by: Basavaiah Kanakapura, et al.
Published: (2004-01-01)

The use of liquid chromatography method for quantitative determination of active substances in Enalapril-H tablets
by: Nataliia Bevz, et al.
Published: (2021-02-01)

Prevalence of Multidrug Efflux Pump Requiring Ciprofloxacin, Ofloxacin and Pefloxacin as Substrates, Among Clinical Isolates of Pseudomonas aeruginosa
by: Omoregie, R., et al.
Published: (2007-01-01)

Desenvolvimento de método analítico por CLAE em comprimidos de Benznidazol para a Doença de Chagas Development of an hplc analytical method for benznidazol tablets for the treatment of chagas disease
by: Ana Luiza Maurer da Silva, et al.
Published: (2007-10-01)

Validation of an HPLC method for the determination of amino acids in feed
by: Jajić Igor, et al.
Published: (2013-01-01)

Development and validation of the HPLC-procedure for the quantitative determination of isosorbide dinitrate in matrix granules
by: D. S. Oleynikov, et al.
Published: (2019-09-01)

Transfer of a Multiclass Method for over 60 Antibiotics in Food from High Resolution to Low Resolution Mass Spectrometry
by: Danilo Giusepponi, et al.
Published: (2019-08-01)

Effective method for the detection of piroxicam in human plasma using HPLC
by: Adriana Maria CALVO, et al.
Published: (2016-01-01)

PHARMACOPOEIAL HPLC METHODOLOGY IMPROVEMENT: A CASE STUDY OF PIROXICAM
by: Mikaelly P. Caet, et al.
Published: (2020-12-01)

Development and Application of an Extraction and Quantitative HPLC Method for Sulforaphene in Radish
by: Hua Beibei, et al.
Published: (2015-09-01)

A novel RP – HPLC methodology for method development and validation of aceclofenac and tizanidine pharmaceutical dosage forms
by: Adilakshmi Nenavath, et al.
Published: (2020-11-01)

Determination of cetirizine in tablets and compounded capsules: comparative study between CE and HPLC
by: Lisiane Bajerski, et al.
Published: (2010-01-01)

Stability indicating RP-HPLC method for simultaneous determination of gatifloxacin and dexamethasone in binary combination
by: Syed Naeem Razzaq, et al.
Published: (2017-04-01)

Development and validation of fluoroquinolone detection method in chicken eggs using high-performance liquid chromatography
by: A. A. Lugovskoy, et al.
Published: (2018-04-01)

Regional variation in the potentially inappropriate first-line use of fluoroquinolones in Canada as a key to antibiotic stewardship? A drug utilization review study
by: Audray St-Jean, et al.
Published: (2021-08-01)

DEVELOPMENT AND VALIDATION OF METHODS FOR QUANTITATIVE DETERMINATION OF TOFIZOPAM AND FENAZEPAM IN TABLETS METHOD OF HIGH-PERFORMANCE LIQUID CHROMATOGRAPHY
by: A. M. LAZITSKAYA, et al.
Published: (2017-06-01)

Simultaneous Determination of Dimethomorph and Chlorothalonil in Pesticide Formulation: HPLC Method Development and Validation
by: Anum Hafeez, Sajid Iqbal, Iffat Abdul Tawab Khan, Abbas Bhutto, Faiza Anwar, Qurrat -ul- Ain
Published: (2019-05-01)

A validated method using RP-HPLC for quantification of reserpine in the Brazilian tree Rauvolfia sellowii Müll. Arg. (Apocynaceae)
by: Leopoldo C. Baratto, et al.
Published: (2012-01-01)

Development and optimization of a HPLC-RI method for the determination of major sugars in apple juice and evaluation of the effect of the ripening stage
by: Acácio Antonio Ferreira Zielinski, et al.
Published: (2014-03-01)

Improvement of Tests for the Control of Impurities in Antimicrobial Medicinal Products by Chromatographic Methods: Ciprofloxacin Case Study
by: S. I. Kuleshova, et al.
Published: (2018-12-01)

Development and validation of a stability indicating HPLC method to determine diltiazem hydrochloride in tablets and compounded capsules
by: Mateus Araújo Castro e Souza, et al.
Published: (2017-07-01)

Development and validation of analytical method by HPLC-DAD for determination of vasodilator active in pharmaceutical ophthalmic forms
by: Aina Liz Alves Cesar, et al.
Published: (2020-08-01)

Determination of Polypeptide Antibiotic Residues in Food of Animal Origin by Ultra-High-Performance Liquid Chromatography-Tandem Mass Spectrometry
by: Tomasz Bladek, et al.
Published: (2020-07-01)

Development of a Novel, Fast, Simple HPLC Method for Determination of Atorvastatin and Its Impurities in Tablets
by: Nataliia Shulyak, et al.
Published: (2021-04-01)

Development and validation of a stability-indicating HPLC method for the determination of buclizine hydrochloride in tablets and oral suspension and its application to dissolution studies
by: Gislaine Kuminek, et al.
Published: (2012-01-01)

Validation of quantitative determination methods of diphenhyramine tablets by high performance liquid chromatography
by: S. L. Zagorodniy, et al.
Published: (2015-04-01)

Evaluating Fluoroquinolone Use in Patients Admitted to the Tuberculosis Outpatient Clinic
by: Sinem İliaz, et al.
Published: (2016-08-01)

A simple reversed phase high-performance liquid chromatography (HPLC) method for determination of in situ gelling curcumin-loaded liquid crystals in in vitro performance tests
by: Bruno Fonseca-Santos, et al.
Published: (2017-11-01)