Soluble Epoxide Hydrolase Inhibition in Liver Diseases: A Review of Current Research and Knowledge Gaps

Soluble Epoxide Hydrolase Inhibition in Liver Diseases: A Review of Current Research and Knowledge Gaps

Emerging evidence suggests that soluble epoxide hydrolase (sEH) inhibition is a valuable therapeutic strategy for the treatment of numerous diseases, including those of the liver. sEH rapidly degrades cytochrome P450-produced epoxygenated lipids (epoxy-fatty acids), which are synthesized from omega-...

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Bibliographic Details
Main Authors:	Jeffrey Warner, Josiah Hardesty, Kara Zirnheld, Craig McClain, Dennis Warner, Irina Kirpich
Format:	Article
Language:	English
Published:	MDPI AG 2020-06-01
Series:	Biology
Subjects:	non-alcoholic liver disease metabolic syndrome fibrosis portal hypertension soluble epoxide hydrolase eicosanoids
Online Access:	https://www.mdpi.com/2079-7737/9/6/124

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