Programmed cell death 10 promotes metastasis and epithelial-mesenchymal transition of hepatocellular carcinoma via PP2Ac-mediated YAP activation

Abstract Tumour metastasis is the main cause of postoperative tumour recurrence and mortality in patients with hepatocellular carcinoma (HCC), but the underlying mechanism remains unclear. Accumulating evidence has demonstrated that programmed cell death 10 (PDCD10) plays an important role in many b...

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Bibliographic Details
Main Authors: Bo Sun, Fang-Jing Zhong, Cong Xu, Yi-Ming Li, Yan-Rong Zhao, Mo-Mo Cao, Lian-Yue Yang
Format: Article
Language:English
Published: Nature Publishing Group 2021-09-01
Series:Cell Death and Disease
Online Access:https://doi.org/10.1038/s41419-021-04139-z