A reporter for tracking the UPR in vivo reveals patterns of temporal and cellular stress during atherosclerotic progression

Progression of human arteriosclerosis is associated with and promoted by induction of the endoplasmic reticulum (ER) stress pathway known as the unfolded protein response (UPR). Most studies that assess UPR markers in atherosclerosis rely on methodologies that suffer from low signal sensitivity, non...

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Bibliographic Details
Main Authors: Edward Thorp, Takao Iwawaki, Masayuki Miura, Ira Tabas
Format: Article
Language:English
Published: Elsevier 2011-05-01
Series:Journal of Lipid Research
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520408892