Supernumerary Molars and Wisdom Tooth Shape Alterations in Patients with Neurofibromatosis Type 1

Objectives: The purpose of the present study was the systematic investigation of numerical and morphological aberrations of teeth in the wisdom teeth region in neurofibromatosis type 1 patients. Material and Methods: The panoramic radiographs of 179 patients were analysed for supernumerary molars a...

Full description

Bibliographic Details
Main Authors: Reinhard E. Friedrich, Anika Reul
Format: Article
Language:English
Published: Stilus Optimus 2017-12-01
Series:eJournal of Oral Maxillofacial Research
Subjects:
Online Access:http://www.ejomr.org/JOMR/archives/2017/4/e5/v8n4e5ht.htm
id doaj-8a26715181754028a216c7d875e2a89d
record_format Article
spelling doaj-8a26715181754028a216c7d875e2a89d2020-11-24T20:52:28ZengStilus OptimuseJournal of Oral Maxillofacial Research2029-283X2017-12-0184e510.5037/jomr.2017.8405Supernumerary Molars and Wisdom Tooth Shape Alterations in Patients with Neurofibromatosis Type 1Reinhard E. FriedrichAnika ReulObjectives: The purpose of the present study was the systematic investigation of numerical and morphological aberrations of teeth in the wisdom teeth region in neurofibromatosis type 1 patients. Material and Methods: The panoramic radiographs of 179 patients were analysed for supernumerary molars and dysplastic wisdom teeth with special reference to facial tumour type. The results were compared to radiographic findings obtained in panoramic radiographs of age- and sex-matched controls. Results: The total number of dysplastic or supernumerary molars was 21 (17 individuals, 4.75%) and predominantly a finding of the maxilla (maxilla: 15, mandible: 1, maxilla and mandible: 1). Differences of dental findings between neurofibromatosis type 1 (NF1) patients (n = 15) and the control group (n = 2) were statistically significant (P < 0.01). All individuals with supernumerary molars were diagnosed as being affected with NF1. This difference achieved statistical significance when it was considered that the event may occur at least once per quadrant, and thus the individual potentially needs to be considered four times (P = 0.0038). Conclusions: This investigation revealed that supernumerary molars and aberrations in wisdom tooth form are more common in patients than in age- and sex-matched controls. There is no association between these findings and a specific feature of the disease, id est facial manifestation of a trigeminal nerve sheath tumour (plexiform neurofibroma). The cause of this phenomenon is unknown. A review of these dental findings on other neurofibromatosis type 1 study groups should be attempted.http://www.ejomr.org/JOMR/archives/2017/4/e5/v8n4e5ht.htmneurofibromatosis type 1plexiform neurofibromasupernumerary teethtooth abnormalitieswisdom tooth
collection DOAJ
language English
format Article
sources DOAJ
author Reinhard E. Friedrich
Anika Reul
spellingShingle Reinhard E. Friedrich
Anika Reul
Supernumerary Molars and Wisdom Tooth Shape Alterations in Patients with Neurofibromatosis Type 1
eJournal of Oral Maxillofacial Research
neurofibromatosis type 1
plexiform neurofibroma
supernumerary teeth
tooth abnormalities
wisdom tooth
author_facet Reinhard E. Friedrich
Anika Reul
author_sort Reinhard E. Friedrich
title Supernumerary Molars and Wisdom Tooth Shape Alterations in Patients with Neurofibromatosis Type 1
title_short Supernumerary Molars and Wisdom Tooth Shape Alterations in Patients with Neurofibromatosis Type 1
title_full Supernumerary Molars and Wisdom Tooth Shape Alterations in Patients with Neurofibromatosis Type 1
title_fullStr Supernumerary Molars and Wisdom Tooth Shape Alterations in Patients with Neurofibromatosis Type 1
title_full_unstemmed Supernumerary Molars and Wisdom Tooth Shape Alterations in Patients with Neurofibromatosis Type 1
title_sort supernumerary molars and wisdom tooth shape alterations in patients with neurofibromatosis type 1
publisher Stilus Optimus
series eJournal of Oral Maxillofacial Research
issn 2029-283X
publishDate 2017-12-01
description Objectives: The purpose of the present study was the systematic investigation of numerical and morphological aberrations of teeth in the wisdom teeth region in neurofibromatosis type 1 patients. Material and Methods: The panoramic radiographs of 179 patients were analysed for supernumerary molars and dysplastic wisdom teeth with special reference to facial tumour type. The results were compared to radiographic findings obtained in panoramic radiographs of age- and sex-matched controls. Results: The total number of dysplastic or supernumerary molars was 21 (17 individuals, 4.75%) and predominantly a finding of the maxilla (maxilla: 15, mandible: 1, maxilla and mandible: 1). Differences of dental findings between neurofibromatosis type 1 (NF1) patients (n = 15) and the control group (n = 2) were statistically significant (P < 0.01). All individuals with supernumerary molars were diagnosed as being affected with NF1. This difference achieved statistical significance when it was considered that the event may occur at least once per quadrant, and thus the individual potentially needs to be considered four times (P = 0.0038). Conclusions: This investigation revealed that supernumerary molars and aberrations in wisdom tooth form are more common in patients than in age- and sex-matched controls. There is no association between these findings and a specific feature of the disease, id est facial manifestation of a trigeminal nerve sheath tumour (plexiform neurofibroma). The cause of this phenomenon is unknown. A review of these dental findings on other neurofibromatosis type 1 study groups should be attempted.
topic neurofibromatosis type 1
plexiform neurofibroma
supernumerary teeth
tooth abnormalities
wisdom tooth
url http://www.ejomr.org/JOMR/archives/2017/4/e5/v8n4e5ht.htm
work_keys_str_mv AT reinhardefriedrich supernumerarymolarsandwisdomtoothshapealterationsinpatientswithneurofibromatosistype1
AT anikareul supernumerarymolarsandwisdomtoothshapealterationsinpatientswithneurofibromatosistype1
_version_ 1716799575709188096