Induction of Broad-Spectrum Protective Immunity against Disparate Cryptococcus Serotypes

Induction of Broad-Spectrum Protective Immunity against Disparate Cryptococcus Serotypes

Cryptococcosis is a fungal disease caused by multiple Cryptococcus serotypes; particularly C. neoformans (serotypes A and D) and C. gattii (serotypes B and C). To date, there is no clinically available vaccine to prevent cryptococcosis. Mice given an experimental pulmonary vaccination with a C. neof...

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Bibliographic Details
Main Authors: Marley C. Caballero Van Dyke, Ashok K. Chaturvedi, Sarah E. Hardison, Chrissy M. Leopold Wager, Natalia Castro-Lopez, Camaron R. Hole, Karen L. Wozniak, Floyd L. Wormley
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-10-01
Series:Frontiers in Immunology
Subjects:
Cryptococcus neoformans
Cryptococcus gattii
cryptococcosis
host–fungal interaction
fungal vaccines
fungal immunology
Online Access:http://journal.frontiersin.org/article/10.3389/fimmu.2017.01359/full

Internet

http://journal.frontiersin.org/article/10.3389/fimmu.2017.01359/full

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