A Blunted Sympathetic Function and an Enhanced Nitrergic Activity Contribute to Reduce Mesenteric Resistance in Hyperthyroidism

A Blunted Sympathetic Function and an Enhanced Nitrergic Activity Contribute to Reduce Mesenteric Resistance in Hyperthyroidism

We aimed to determine whether an experimental model of hyperthyroidism could alter the function of sympathetic and nitrergic components of mesenteric innervation. For this purpose, male Wistar rats were divided into (1) control rats (CT) and (2) rats infused with L-Thyroxine (HT). Body weight gain a...

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Bibliographic Details
Main Authors: Laia Cros-Brunsó, Laura Camacho-Rodríguez, Ángel Martínez-González, Pablo Llévenes, Mercedes Salaices, Ana Belen García-Redondo, Javier Blanco-Rivero
Format: Article
Language:English
Published: MDPI AG 2021-01-01
Series:International Journal of Molecular Sciences
Subjects:
hyperthyroidism
rat mesenteric artery
perivascular innervation
noradrenaline
neuronal nitric oxide
protein kinase C
Online Access:https://www.mdpi.com/1422-0067/22/2/570

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