Therapeutic Hypothermia Improves Hind Limb Motor Outcome and Attenuates Oxidative Stress and Neuronal Damage in the Lumbar Spinal Cord Following Cardiac Arrest

Therapeutic Hypothermia Improves Hind Limb Motor Outcome and Attenuates Oxidative Stress and Neuronal Damage in the Lumbar Spinal Cord Following Cardiac Arrest

Hypothermia enhances outcomes of patients after resuscitation after cardiac arrest (CA). However, the underlying mechanism is not fully understood. In this study, we investigated effects of hypothermic therapy on neuronal damage/death, microglial activation, and changes of endogenous antioxidants in...

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Bibliographic Details
Main Authors: Ji Hyeon Ahn, Tae-Kyeong Lee, Bora Kim, Jae-Chul Lee, Hyun-Jin Tae, Jeong Hwi Cho, Yoonsoo Park, Myoung Cheol Shin, Taek Geun Ohk, Chan Woo Park, Jun Hwi Cho, Seongkweon Hong, Joon Ha Park, Soo Young Choi, Moo-Ho Won
Format: Article
Language:English
Published: MDPI AG 2020-01-01
Series:Antioxidants
Subjects:
antioxidants
asphyxial cardiac arrest
hypothermia
lumbar spinal cord
motor neurons
neuroprotection
oxidative stress
Online Access:https://www.mdpi.com/2076-3921/9/1/38

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