The Plasminogen Receptor, Plg-RKT, and Macrophage Function
When plasminogen binds to cells its activation to plasmin is markedly enhanced compared to the reaction in solution. Thus, cells become armed with the broad spectrum proteolytic activity of plasmin. Cell-surface plasmin plays a key role in macrophage recruitment during the inflammatory response. Pro...
Main Authors: | Lindsey A. Miles, Shahrzad Lighvani, Nagyung Baik, Nicholas M. Andronicos, Emily I. Chen, Caitlin M. Parmer, Sophia Khaldoyanidi, Jenna E. Diggs, William B. Kiosses, Mark P. Kamps, John R. Yates, Robert J. Parmer |
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Format: | Article |
Language: | English |
Published: |
Hindawi Limited
2012-01-01
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Series: | Journal of Biomedicine and Biotechnology |
Online Access: | http://dx.doi.org/10.1155/2012/250464 |
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