The Plasminogen Receptor, Plg-RKT, and Macrophage Function

The Plasminogen Receptor, Plg-RKT, and Macrophage Function

When plasminogen binds to cells its activation to plasmin is markedly enhanced compared to the reaction in solution. Thus, cells become armed with the broad spectrum proteolytic activity of plasmin. Cell-surface plasmin plays a key role in macrophage recruitment during the inflammatory response. Pro...

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Bibliographic Details
Main Authors: Lindsey A. Miles, Shahrzad Lighvani, Nagyung Baik, Nicholas M. Andronicos, Emily I. Chen, Caitlin M. Parmer, Sophia Khaldoyanidi, Jenna E. Diggs, William B. Kiosses, Mark P. Kamps, John R. Yates, Robert J. Parmer
Format: Article
Language:English
Published: Hindawi Limited 2012-01-01
Series:Journal of Biomedicine and Biotechnology
Online Access:http://dx.doi.org/10.1155/2012/250464

Internet

http://dx.doi.org/10.1155/2012/250464

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