Investigating the Roles of the C-Terminal Domain of Plasmodium falciparum GyrA.

Malaria remains as one of the most deadly diseases in developing countries. The Plasmodium causative agents of human malaria such as Plasmodium falciparum possess an organelle, the apicoplast, which is the result of secondary endosymbiosis and retains its own circular DNA. A type II topoisomerase, D...

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Bibliographic Details
Main Authors: Soshichiro Nagano, Eiko Seki, Ting-Yu Lin, Mikako Shirouzu, Shigeyuki Yokoyama, Jonathan G Heddle
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4643928?pdf=render