CIRBP Knockdown Attenuates Tumourigenesis and Improves the Chemosensitivity of Pancreatic Cancer via the Downregulation of DYRK1B

CIRBP Knockdown Attenuates Tumourigenesis and Improves the Chemosensitivity of Pancreatic Cancer via the Downregulation of DYRK1B

Pancreatic ductal adenocarcinoma (PDAC) is one of the most lethal malignancies worldwide with very limited treatment options. Cold-inducible RNA binding protein (CIRBP) plays promoting roles in several types of cancers, but its function remains unclear in PDAC. Here, we found that the expression of...

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Bibliographic Details
Main Authors:	Xiang Chen, Hongyu Xie, Xin Wang, Zhinan Zheng, Sanqing Jin
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2021-08-01
Series:	Frontiers in Cell and Developmental Biology
Subjects:	cold-inducible RNA binding protein pancreatic ductal adenocarcinoma dormancy tumorigenesis chemoresistance
Online Access:	https://www.frontiersin.org/articles/10.3389/fcell.2021.667551/full

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