ISN Forefronts Symposium 2015: The Diverse Function of Macrophages in Renal Disease

Experimental and human studies indicate that macrophages play a key role within the diseased kidney and represent a target for novel therapies. This brief review outlines the involvement and nature of macrophages in renal disease and highlights the phenotypic plasticity of these cells and their resp...

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Main Authors: Fiona Duthie, Eoin D. O’Sullivan, Jeremy Hughes
Format: Article
Language:English
Published: Elsevier 2016-09-01
Series:Kidney International Reports
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2468024916300560
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spelling doaj-89dcca46ee324f079b357b0d39c70cdf2020-11-24T23:21:31ZengElsevierKidney International Reports2468-02492016-09-011320420910.1016/j.ekir.2016.08.004ISN Forefronts Symposium 2015: The Diverse Function of Macrophages in Renal DiseaseFiona Duthie0Eoin D. O’Sullivan1Jeremy Hughes2Department of Renal Medicine, Royal Infirmary of Edinburgh, Edinburgh, UKDepartment of Renal Medicine, Royal Infirmary of Edinburgh, Edinburgh, UKDepartment of Renal Medicine, Royal Infirmary of Edinburgh, Edinburgh, UKExperimental and human studies indicate that macrophages play a key role within the diseased kidney and represent a target for novel therapies. This brief review outlines the involvement and nature of macrophages in renal disease and highlights the phenotypic plasticity of these cells and their responsiveness to the renal microenvironment.http://www.sciencedirect.com/science/article/pii/S2468024916300560fibrosisinflammationkidneymacrophage
collection DOAJ
language English
format Article
sources DOAJ
author Fiona Duthie
Eoin D. O’Sullivan
Jeremy Hughes
spellingShingle Fiona Duthie
Eoin D. O’Sullivan
Jeremy Hughes
ISN Forefronts Symposium 2015: The Diverse Function of Macrophages in Renal Disease
Kidney International Reports
fibrosis
inflammation
kidney
macrophage
author_facet Fiona Duthie
Eoin D. O’Sullivan
Jeremy Hughes
author_sort Fiona Duthie
title ISN Forefronts Symposium 2015: The Diverse Function of Macrophages in Renal Disease
title_short ISN Forefronts Symposium 2015: The Diverse Function of Macrophages in Renal Disease
title_full ISN Forefronts Symposium 2015: The Diverse Function of Macrophages in Renal Disease
title_fullStr ISN Forefronts Symposium 2015: The Diverse Function of Macrophages in Renal Disease
title_full_unstemmed ISN Forefronts Symposium 2015: The Diverse Function of Macrophages in Renal Disease
title_sort isn forefronts symposium 2015: the diverse function of macrophages in renal disease
publisher Elsevier
series Kidney International Reports
issn 2468-0249
publishDate 2016-09-01
description Experimental and human studies indicate that macrophages play a key role within the diseased kidney and represent a target for novel therapies. This brief review outlines the involvement and nature of macrophages in renal disease and highlights the phenotypic plasticity of these cells and their responsiveness to the renal microenvironment.
topic fibrosis
inflammation
kidney
macrophage
url http://www.sciencedirect.com/science/article/pii/S2468024916300560
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AT jeremyhughes isnforefrontssymposium2015thediversefunctionofmacrophagesinrenaldisease
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