ISN Forefronts Symposium 2015: The Diverse Function of Macrophages in Renal Disease

Experimental and human studies indicate that macrophages play a key role within the diseased kidney and represent a target for novel therapies. This brief review outlines the involvement and nature of macrophages in renal disease and highlights the phenotypic plasticity of these cells and their resp...

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Bibliographic Details
Main Authors: Fiona Duthie, Eoin D. O’Sullivan, Jeremy Hughes
Format: Article
Language:English
Published: Elsevier 2016-09-01
Series:Kidney International Reports
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2468024916300560
Description
Summary:Experimental and human studies indicate that macrophages play a key role within the diseased kidney and represent a target for novel therapies. This brief review outlines the involvement and nature of macrophages in renal disease and highlights the phenotypic plasticity of these cells and their responsiveness to the renal microenvironment.
ISSN:2468-0249