HDAC Inhibitors and RECK Modulate Endoplasmic Reticulum Stress in Tumor Cells

HDAC Inhibitors and RECK Modulate Endoplasmic Reticulum Stress in Tumor Cells

In the tumor microenvironment hypoxia and nutrient deprived states can induce endoplasmic reticulum (ER) stress. If ER stress is not relieved, the tumor cells may become apoptotic. Therefore, targeting ER homeostasis is a potential strategy for cancer treatment. Various chemotherapeutic agents inclu...

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Bibliographic Details
Main Authors:	Yun Chen, Ya-Hui Tsai, Sheng-Hong Tseng
Format:	Article
Language:	English
Published:	MDPI AG 2017-01-01
Series:	International Journal of Molecular Sciences
Subjects:	histone deacetylase inhibitors reversion-inducing cysteine-rich protein with Kazal motifs endoplasmic reticulum stress cancers
Online Access:	http://www.mdpi.com/1422-0067/18/2/258

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