É-Conotoxins GVIA, MVIIA and CVID: SAR and Clinical Potential

Abstract: Highly selective N-type voltage-gated calcium (CaV) channel inhibitors from cone snail venom (the É-conotoxins) have emerged as a new class of therapeutics for the treatment of chronic and neuropathic pain. Earlier in 2005, Prialt (Elan) or synthetic É-conotoxin MVIIA, was the first ÃÂ...

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Bibliographic Details
Main Authors: Richard J. Lewis, Christina I. Schroeder
Format: Article
Language:English
Published: MDPI AG 2006-04-01
Series:Marine Drugs
Subjects:
Online Access:http://www.mdpi.com/1660-3397/4/3/193/