Outlook: Membrane junctions enable the metabolic trapping of fatty acids by intracellular acyl-CoA synthetases

The mechanism of fatty acid uptake is of high interest for basic research and clinical interventions. Recently we showed that mammalian long chain fatty acyl-CoA synthetases (ACS) are not only essential enzymes for lipid metabolism but are also involved in cellular fatty acid uptake. Overexpression,...

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Bibliographic Details
Main Authors: Joachim eFuellekrug, Robert eEhehalt, Margarete ePoppelreuther
Format: Article
Language:English
Published: Frontiers Media S.A. 2012-10-01
Series:Frontiers in Physiology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fphys.2012.00401/full