Rapid evolution of the human mutation spectrum
DNA is a remarkably precise medium for copying and storing biological information. This high fidelity results from the action of hundreds of genes involved in replication, proofreading, and damage repair. Evolutionary theory suggests that in such a system, selection has limited ability to remove gen...
Main Authors: | Kelley Harris, Jonathan K Pritchard |
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Format: | Article |
Language: | English |
Published: |
eLife Sciences Publications Ltd
2017-04-01
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Series: | eLife |
Subjects: | |
Online Access: | https://elifesciences.org/articles/24284 |
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