Systematic Profiling of the Multicomponents and Authentication of Erzhi Pill by UHPLC/Q-Orbitrap-MS Oriented Rapid Polarity-Switching Data-Dependent Acquisition and Selective Monitoring of the Chemical Markers Deduced from Fingerprint Analysis

Systematic Profiling of the Multicomponents and Authentication of Erzhi Pill by UHPLC/Q-Orbitrap-MS Oriented Rapid Polarity-Switching Data-Dependent Acquisition and Selective Monitoring of the Chemical Markers Deduced from Fingerprint Analysis

The analytical platform UHPLC/Q-Orbitrap-MS offers a solution to quality investigation of TCM with high definiteness. Using Erzhi Pill (EZP) as a case, we developed UHPLC/Q-Orbitrap-MS based approaches to achieve systematic multicomponent identification and rapid authentication. Comprehensive multic...

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Bibliographic Details
Main Authors: Li Jia, Lingling Fu, Xiaoyan Wang, Wenzhi Yang, Hongda Wang, Tiantian Zuo, Chunxia Zhang, Ying Hu, Xiumei Gao, Lifeng Han
Format: Article
Language:English
Published: MDPI AG 2018-11-01
Series:Molecules
Subjects:
Erzhi Pill
UHPLC/Q-Orbitrap-MS
polarity-switching data-dependent acquisition
identity marker
authentication
selective ion monitoring
Online Access:https://www.mdpi.com/1420-3049/23/12/3143

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