CXCR4 Antagonists as Stem Cell Mobilizers and Therapy Sensitizers for Acute Myeloid Leukemia and Glioblastoma?

Glioblastoma is the most aggressive and malignant primary brain tumor in adults and has a poor patient survival of only 20 months after diagnosis. This poor patient survival is at least partly caused by glioblastoma stem cells (GSCs), which are slowly-dividing and therefore therapy-resistant. GSCs a...

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Bibliographic Details
Main Authors: Vashendriya V.V. Hira, Cornelis J.F. Van Noorden, Remco J. Molenaar
Format: Article
Language:English
Published: MDPI AG 2020-02-01
Series:Biology
Subjects:
Online Access:https://www.mdpi.com/2079-7737/9/2/31