Advances in immunological treatment of autoimmune hepatitis

Advances in immunological treatment of autoimmune hepatitis

In recent years, autoimmune hepatitis (AIH) has attracted more and more attention due to its unique clinicopathological features. However, its incidence and clinical features remain unclear, and systematic and in-depth studies are still needed. This article reviews the epidemiology, etiology, pathog...

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Main Authors: ZHANG Jun, WANG Qixia, MA Xiong
Format: Article
Language:zho
Published: Editorial Department of Journal of Clinical Hepatology 2016-10-01
Series:Linchuang Gandanbing Zazhi
Online Access:http://www.lcgdbzz.org/qk_content.asp?id=7735
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spelling doaj-897b275c65e94db6af650a24f68dabe12020-11-24T22:45:20ZzhoEditorial Department of Journal of Clinical HepatologyLinchuang Gandanbing Zazhi1001-52561001-52562016-10-0132101874187710.3969/j.issn.1001-5256.2016.10.010Advances in immunological treatment of autoimmune hepatitisZHANG Jun0WANG Qixia1MA Xiong2Department of Gastroenterology, Renji Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai Institute of Digestive Disease, Shanghai 200001, ChinaDepartment of Gastroenterology, Renji Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai Institute of Digestive Disease, Shanghai 200001, ChinaDepartment of Gastroenterology, Renji Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai Institute of Digestive Disease, Shanghai 200001, ChinaIn recent years, autoimmune hepatitis (AIH) has attracted more and more attention due to its unique clinicopathological features. However, its incidence and clinical features remain unclear, and systematic and in-depth studies are still needed. This article reviews the epidemiology, etiology, pathogenesis, clinical features, and diagnosis and treatment of AIH and points out that clinical studies or animal models of AIH have proved the effects of TNF-α neutralizing antibody, rituximab, all-trans retinoic acid, and regulatory T cell transplantation in the treatment of AIH.http://www.lcgdbzz.org/qk_content.asp?id=7735
collection DOAJ
language zho
format Article
sources DOAJ
author ZHANG Jun
WANG Qixia
MA Xiong
spellingShingle ZHANG Jun
WANG Qixia
MA Xiong
Advances in immunological treatment of autoimmune hepatitis
Linchuang Gandanbing Zazhi
author_facet ZHANG Jun
WANG Qixia
MA Xiong
author_sort ZHANG Jun
title Advances in immunological treatment of autoimmune hepatitis
title_short Advances in immunological treatment of autoimmune hepatitis
title_full Advances in immunological treatment of autoimmune hepatitis
title_fullStr Advances in immunological treatment of autoimmune hepatitis
title_full_unstemmed Advances in immunological treatment of autoimmune hepatitis
title_sort advances in immunological treatment of autoimmune hepatitis
publisher Editorial Department of Journal of Clinical Hepatology
series Linchuang Gandanbing Zazhi
issn 1001-5256
1001-5256
publishDate 2016-10-01
description In recent years, autoimmune hepatitis (AIH) has attracted more and more attention due to its unique clinicopathological features. However, its incidence and clinical features remain unclear, and systematic and in-depth studies are still needed. This article reviews the epidemiology, etiology, pathogenesis, clinical features, and diagnosis and treatment of AIH and points out that clinical studies or animal models of AIH have proved the effects of TNF-α neutralizing antibody, rituximab, all-trans retinoic acid, and regulatory T cell transplantation in the treatment of AIH.
url http://www.lcgdbzz.org/qk_content.asp?id=7735
work_keys_str_mv AT zhangjun advancesinimmunologicaltreatmentofautoimmunehepatitis
AT wangqixia advancesinimmunologicaltreatmentofautoimmunehepatitis
AT maxiong advancesinimmunologicaltreatmentofautoimmunehepatitis
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