Nicotinamide phosphoribosyltransferase expression and clinical outcome of resected stage I/II pancreatic ductal adenocarcinoma.

Nicotinamide phosphoribosyltransferase expression and clinical outcome of resected stage I/II pancreatic ductal adenocarcinoma.

<h4>Background</h4>Nicotinamide phosphoribosyltransferase (NAMPT) plays a key role in the biosynthesis of nicotinamide adenine dinucleotide (NAD+), which is a vital cofactor in redox reactions and a substrate for NAD+ consuming enzymes including CD38, PARPs and sirtuins. NAMPT over-expre...

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Bibliographic Details
Main Authors: Katelynn Davis, Craig D Dunseth, Sarah L Mott, Kimberly L Cramer-Morales, Ann M Miller, Po Hien Ear, James J Mezhir, Andrew M Bellizzi, Carlos H F Chan
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0213576

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https://doi.org/10.1371/journal.pone.0213576

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