Mitochondrial membrane peroxidizability index is inversely related to maximum life span in mammals

The oxidative stress theory of aging predicts a low degree of fatty acid unsaturation in tissues of longevous animals, because membrane lipids increase their sensitivity to oxidative damage as a function of their unsaturation. Accordingly, the fatty acids analyses of liver mitochondria from eight ma...

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Bibliographic Details
Main Authors: Reinald Pamplona, Manuel Portero-Otín, David Riba, Cristina Ruiz, Joan Prat, Maria Josep Bellmunt, Gustavo Barja
Format: Article
Language:English
Published: Elsevier 1998-10-01
Series:Journal of Lipid Research
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520324974