Effective neuroprotection and organ protection: activation of the endogenous mechanisms of sanogenesis
The review sets out modern ideas about the mechanisms of action of gamma-aminobutyric acid (GABA) in the central nervous system and other organs and systems. Current experimental and clinical studies have shown that GABA has numerous effects: neuroprotective, antihypertensive, antidiabetic, antitumo...
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Online Access: | https://nnp.ima-press.net/nnp/article/view/1376 |
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doaj-894fc7eeb00d47caa54f8c90b73151b42021-07-29T08:58:41ZrusIMA-PRESS LLCNevrologiâ, Nejropsihiatriâ, Psihosomatika2074-27112310-13422020-06-0112312312710.14412/2074-2711-2020-3-123-1271007Effective neuroprotection and organ protection: activation of the endogenous mechanisms of sanogenesisR. G. Esin0O. R. Esin1A. R. Khakimova2Kazan State Medical Academy, Branch, Russian Medical Academy of Continuing Professional Education, Ministry of Health of Russia; Kazan (Volga) Federal University, Ministry of Education and Science of RussiaKazan (Volga) Federal University, Ministry of Education and Science of RussiaKazan State Medical Academy, Branch, Russian Medical Academy of Continuing Professional Education, Ministry of Health of RussiaThe review sets out modern ideas about the mechanisms of action of gamma-aminobutyric acid (GABA) in the central nervous system and other organs and systems. Current experimental and clinical studies have shown that GABA has numerous effects: neuroprotective, antihypertensive, antidiabetic, antitumor, anti-inflammatory, antimicrobial, anti-allergic, hepatoprotective, nephroprotective and enteroprotective, and others, which are currently the subject for study by biologists, physiologists, and physicians. Synthetic GABA analogues are widely used in clinical practice. One of these drugs is aminophenylbutyric acid hydrochloride (Anvifen®) that has demonstrated high efficiency and safety in clinical practice.https://nnp.ima-press.net/nnp/article/view/1376gamma-aminobutyric acidaminophenylbutyric acid hydrochlorideanvifen®neuroprotectioncytoprotection |
collection |
DOAJ |
language |
Russian |
format |
Article |
sources |
DOAJ |
author |
R. G. Esin O. R. Esin A. R. Khakimova |
spellingShingle |
R. G. Esin O. R. Esin A. R. Khakimova Effective neuroprotection and organ protection: activation of the endogenous mechanisms of sanogenesis Nevrologiâ, Nejropsihiatriâ, Psihosomatika gamma-aminobutyric acid aminophenylbutyric acid hydrochloride anvifen® neuroprotection cytoprotection |
author_facet |
R. G. Esin O. R. Esin A. R. Khakimova |
author_sort |
R. G. Esin |
title |
Effective neuroprotection and organ protection: activation of the endogenous mechanisms of sanogenesis |
title_short |
Effective neuroprotection and organ protection: activation of the endogenous mechanisms of sanogenesis |
title_full |
Effective neuroprotection and organ protection: activation of the endogenous mechanisms of sanogenesis |
title_fullStr |
Effective neuroprotection and organ protection: activation of the endogenous mechanisms of sanogenesis |
title_full_unstemmed |
Effective neuroprotection and organ protection: activation of the endogenous mechanisms of sanogenesis |
title_sort |
effective neuroprotection and organ protection: activation of the endogenous mechanisms of sanogenesis |
publisher |
IMA-PRESS LLC |
series |
Nevrologiâ, Nejropsihiatriâ, Psihosomatika |
issn |
2074-2711 2310-1342 |
publishDate |
2020-06-01 |
description |
The review sets out modern ideas about the mechanisms of action of gamma-aminobutyric acid (GABA) in the central nervous system and other organs and systems. Current experimental and clinical studies have shown that GABA has numerous effects: neuroprotective, antihypertensive, antidiabetic, antitumor, anti-inflammatory, antimicrobial, anti-allergic, hepatoprotective, nephroprotective and enteroprotective, and others, which are currently the subject for study by biologists, physiologists, and physicians. Synthetic GABA analogues are widely used in clinical practice. One of these drugs is aminophenylbutyric acid hydrochloride (Anvifen®) that has demonstrated high efficiency and safety in clinical practice. |
topic |
gamma-aminobutyric acid aminophenylbutyric acid hydrochloride anvifen® neuroprotection cytoprotection |
url |
https://nnp.ima-press.net/nnp/article/view/1376 |
work_keys_str_mv |
AT rgesin effectiveneuroprotectionandorganprotectionactivationoftheendogenousmechanismsofsanogenesis AT oresin effectiveneuroprotectionandorganprotectionactivationoftheendogenousmechanismsofsanogenesis AT arkhakimova effectiveneuroprotectionandorganprotectionactivationoftheendogenousmechanismsofsanogenesis |
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1721250518074916864 |